An experimental dental caries model using inbred mouse strains.
نویسندگان
چکیده
منابع مشابه
Dental fluorosis: variability among different inbred mouse strains.
Concurrent with the decline in dental caries has been an increase in the prevalence of dental fluorosis, a side-effect of exposure to greater than optimal levels of fluoride during amelogenesis. The mechanisms that underlie the pathogenesis of dental fluorosis are not known. We hypothesize that genetic determinants influence an individual's susceptibility or resistance to develop dental fluoros...
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The recombinant inbred mouse strain, SWXL-4, exhibits tonic-clonic and generalized seizures similar to the commonest epilepsies in humans. In SWXL-4 animals, seizures are observed following routine handling at about 80 days of age and may be induced as early as 55 days by rhythmic gentle tossing. Seizures are accompanied by rapid, bilateral high frequency spike cortical discharges and followed ...
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In recent years, genetic studies in humans have identified a handful of genes that are associated with common disorders, but our understanding of such diseases at the genetic level remains relatively rudimentary. The use of mice to dissect the complex genetic etiology of common disorders offers a viable alternative to human studies since experimental parameters, such as environmental influences...
متن کاملOrigin of inbred NZ mouse strains.
Inbreeding of mice was begun in 1948 in our labora tories in response to the request of Dr. Franz Bielschow sky, who recognized the need for genetically and nutri tionally uniform animals for cancer research. The resulting strains of inbred NZ mice proved useful for research in immunology, biochemistry, and other fields, and they have been widely distributed. We often have inquiries from invest...
متن کاملIntraocular pressure in inbred mouse strains.
PURPOSE To develop a protocol to measure the intraocular pressure (IOP) of living mice and to determine the IOP of genetically different mouse strains. METHODS Eyes of anesthetized animals were cannulated with a very fine fluid-filled glass microneedle. The microneedle was connected to a pressure transducer, and the pressure signal was analyzed with a computer system. Intraocular pressures of...
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ژورنال
عنوان ژورنال: Japanese Journal of Oral Biology
سال: 1991
ISSN: 0385-0137
DOI: 10.2330/joralbiosci1965.33.46